DS-01 Daily Synbiotic

Probiotic Strains

DS-01 is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.

Digestive Health / Immune / Gut Barrier Complex (38.7 billion AFU):
Contains 16 strains including Bifidobacterium longum and Lactobacillus plantarum, specifically designed to improve digestive discomfort.

Skin Health Complex (3.34 billion AFU):
4 strains support the gut-epidermal axis, improving skin condition.

Cardiovascular Health Complex (4.21 billion AFU):
2 strains help maintain cholesterol balance.

Micronutrient Synthesis Complex (7.32 billion AFU):
2 strains aid in the synthesis of vitamins and other nutrients,Also helps improve the intestinal absorption efficiency of minerals (iron, calcium, zinc).

Prebiotics and other ingredients

  • Prebiotics:
    400 mg Punica granatum extract (containing >40% patented MAPP ingredient, a polyphenolic active substance) provides exclusive nutrition for beneficial bacteria. Non-fiber-based prebiotic (unlike common food-derived prebiotics).
  • Other Ingredients:
    Vegetarian capsules (outer capsule: hydroxypropyl methylcellulose, chlorophyll; inner capsule: hydroxypropyl methylcellulose, water), organic rice fiber, organic rice extract; free of preservatives and binders.

Exclusive Delivery System

ViaCap Dual-Capsule Delivery Technology:
This is another technology Seed is proud of, called “ViaCap.” It is a double-layered capsule made from seaweed polysaccharides.

  • Probiotic Inner Capsule

    Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and free of all 14 classes of allergens identified by the European Food Safety Authority (EFSA).

  • Prebiotic Outer Capsule

    Our prebiotic formula consists of pungent glycosides (containing >40% polyphenolic active substances) concentrated from Indian pomegranates—which are biotransformed by gut microbiota into potent metabolites beneficial to human health.

    Many probiotics don’t make it to the gut alive. DS-01 does.

    ViaCap Technology
    Our proprietary dual-capsule system is built for a timed release to the colon: the prebiotic outer capsule releases in the upper GI tract and the probiotic inner capsule continues to the large intestine.

    • Outer capsule made from cellulose protects probiotics and prebiotics as they travel through the GI tract.
    • Plant-based formula—no synthetic coatings like similar cap-in-cap systems.
    • Engineered for precision delivery to the colon, where bacteria is needed to work effectively.

    Survivability

    Many probiotics—like gummies, powders, and drinks—dissolve during digestion. DS-01’s proprietary ViaCap system is engineered to protect probiotic strains from stomach acid, digestive enzymes, and bile.


    Digestive Survivability Testing (SHIME)
    To evaluate the survival of our probiotics, we use a Simulator of the Human Intestinal Microbial Ecosystem (SHIME)—the closest simulation of the human gastrointestinal system. It recreates the physiological conditions of digestion (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids) and time spent in each step to represent the dynamic microbial conditions of the human gastrointestinal tract.

    24 Diverse Probiotic Strains

    Research-derived doses for microbial diversity, the foundation of a healthy gut.

    Engineered to Survive

    Proprietary ViaCap technology safeguards probiotics during the journey to the colon.

    Antioxidant-Promoting Prebiotic

    Non-fiber based prebiotic (unlike many found in food or drinks) that feeds beneficial gut microbes.

    4 Gold-Standard Clinical Trials

    After four scientific verifications by experts, the complete and effective formula has been confirmed.

    The DS-01 Difference

    Our formulation prioritizes strain diversity and survivability, so you get clinically proven results, not empty promises.

    DS-01 Daily Probiotics Clinical Trial

     

    Clinical Trials

    Only about 16% of supplements are clinically tested.DS-01® has been clinically proven in 4 gold-standard, double-blind placebo controlled clinical trials.In addition, DS-01®’s probiotic strains have been validated in 10, dose-matched gold-standard clinical trials.
    The Impact of Clinical Proof
    Double-blind, randomized, placebo-controlled trials (DBRCTs) are the gold standard in scientific research for various reasons, including:

    • Bias elimination
    • Control for placebo-effect
    • Validated efficacy
    • Regulatory compliance

    By testing DS-01 as a full formulation, the entire product is meticulously inspected and validated for safety, tolerability, and efficacy.

    Digestive Health

    DS-01 is formulated to improve the frequency of your bowel movements, as well as increase stool consistency and comfort during evacuation.

    Clinical Trial Results

    • In a 30-Day Study on select DS-01 strains, adults experiencing gastrointestinal troubles saw significant improvement in bowel movement frequency, consistency, and ease of defecation, compared to placebo.

    • DS-01's strains also demonstrated improvements in burning, discomfort, sense of complete emptying, and abdominal bloating.

    Immune Health

    DS-01 promotes a strong, resilient immune system. Dedicated strains support the gut-immune axis, which allows these systems to communicate effectively and strengthen overall immune function.

    Clinical Trial Results

    • In a 12-week study using select DS-01 strains, participants showed a reduction in microbial translocation across the intestinal epithelial barrier and favorable circulating Th17:Treg and Th1:Th2 ratios. These findings indicate an appropriately responsive immunologic profile.

    Skin Health

    DS-01 is formulated with dedicated strains that support the gut-skin axis, which plays a key role in regulating inflammatory pathways between the gut and skin.
    Clinical Trial Results

    • A 4-week study found DS-01's prebiotic significantly reduced wrinkle severity and demonstrated an overall shift in the skin microbiome, indicating a beneficial effect on the gut-skin axis.
    • A 12-week study of adults with functionally and aesthetically bothersome skin showed DS-01 strains not only improved skin appearance, but also raised quality of life scores.

    Heart Health

    DS-01 is formulated to help maintain healthy, in-range cholesterol and blood pressure levels. Select strains promote the production of beneficial metabolites in the gut, which supports healthy liver function and cholesterol balance.
    Clinical Trial Results

    • In a 12-week study, DS-01 strains helped probiotic group participants maintain healthy, baseline LDL-C levels, compared to a placebo group that experienced LDL-C increases.
    • Additionally, the probiotic group demonstrated reinforcement of HDL-cholesterol and evidence of healthy triglyceride management within the 6-12 week timeframe.

    Gut Barrier

    DS-01 is formulated to strengthen and support a resilient gut barrier. Select strains replenish microflora in the gut in order to help rebuild a weakened microbiome.
    Clinical Trial Results

    • In a 12-week study using select DS-01 strains, adults experiencing increased gut permeability showed significant reductions in circulating lipopolysaccharide (LPS), a marker of increased epithelial permeability, the cells which comprise the gut barrier.
    • DS-01 significantly reduced urinary lactulose excretion starting at 7 days and after 3 months of ongoing DS-01 use, compared to the placebo group— indicating both immediate and continued support for gut barrier integrity and function.
    Come and see