Chelsea.
Verified Customer
Since starting my DS-01Daily Synbiotic a little over a year ago, my gut and quality of life have drastically improved. I rarely bloat, my bathroom schedule is regular, and my skin/hair/nails are even thriving. I recommend Seed to everyone.
DS-01 Daily Synbiotic
DS-01 Daily Synbiotic
Regular price
$43.99
Regular price
$43.99
Sale price
$63.00
Unit price
per
The clinically proven, 24 strain probiotic + prebiotic for daily gut health, digestive relief, and whole body benefits.
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Proprietary DS-01 strain library
Proprietary DS-01 strain library
Instead of using commercially available strains, Seed uses 24 highly active, clinically tested bacterial strains selected by its scientific committee.
- Clear Origin: All strains are labeled with their origin (primarily isolated from the intestines of healthy humans) and have a strain number (e.g., Lactobacillus plantarum Lp-115).
Targeted Functions:
Targeted Functions:
These 24 strains were divided into two main functional groups:
Digestive Health: Helps maintain a healthy intestinal barrier function, supports intestinal motility, and promotes nutrient absorption.
Overall Health: This is a key focus of Seed's marketing, including supporting skin health (through the gut-epidermal axis), cardiovascular health (through the metabolism of dietary fiber to produce short-chain fatty acids), and immune system function.
The complete probiotic that delivers results in just 7 days
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Within One Week:
Reduces bleeding and bloating and improves gut health within one week.
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Four weeks:
Effective elimination of metabolic waste leads to smoother, clearer skin.
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Three months:
Boosts the immune system, improves skin and heart health
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Ongoing:
Restores gut microbiota and strengthens the gut barrier function.
DS-01 Daily Synbiotic
Probiotic Strains
DS-01 is formulated with 24 scientifically and clinically studied probiotic strains and a patented, non-fermenting prebiotic.
53.6 billion AFU. No refrigeration required.
Prebiotics and other ingredients
- Prebiotics:
400 mg Punica granatum extract (containing >40% patented MAPP ingredient, a polyphenolic active substance) provides exclusive nutrition for beneficial bacteria. Non-fiber-based prebiotic (unlike common food-derived prebiotics). - Other Ingredients:
Vegetarian capsules (outer capsule: hydroxypropyl methylcellulose, chlorophyll; inner capsule: hydroxypropyl methylcellulose, water), organic rice fiber, organic rice extract; free of preservatives and binders.
Exclusive Delivery System
ViaCap Dual-Capsule Delivery Technology:
This is another technology Seed is proud of, called “ViaCap.” It is a double-layered capsule made from seaweed polysaccharides.
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Probiotic Inner Capsule
Proprietary formulation consisting of 24 probiotic strains (53.6 billion AFU) validated through strain-specific research and free of all 14 classes of allergens identified by the European Food Safety Authority (EFSA).
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Prebiotic Outer Capsule
Our prebiotic formula consists of pungent glycosides (containing >40% polyphenolic active substances) concentrated from Indian pomegranates—which are biotransformed by gut microbiota into potent metabolites beneficial to human health.
24 Diverse Probiotic Strains
Research-derived doses for microbial diversity, the foundation of a healthy gut.
Engineered to Survive
Proprietary ViaCap technology safeguards probiotics during the journey to the colon.
Antioxidant-Promoting Prebiotic
Non-fiber based prebiotic (unlike many found in food or drinks) that feeds beneficial gut microbes.
4 Gold-Standard Clinical Trials
After four scientific verifications by experts, the complete and effective formula has been confirmed.
The DS-01 Difference
Many probiotics don’t make it to the gut alive. DS-01 does.
ViaCap Technology
Our proprietary dual-capsule system is built for a timed release to the colon: the prebiotic outer capsule releases in the upper GI tract and the probiotic inner capsule continues to the large intestine.
- Outer capsule made from cellulose protects probiotics and prebiotics as they travel through the GI tract.
- Plant-based formula—no synthetic coatings like similar cap-in-cap systems.
- Engineered for precision delivery to the colon, where bacteria is needed to work effectively.
Survivability
Many probiotics—like gummies, powders, and drinks—dissolve during digestion. DS-01’s proprietary ViaCap system is engineered to protect probiotic strains from stomach acid, digestive enzymes, and bile.
Digestive Survivability Testing (SHIME)
To evaluate the survival of our probiotics, we use a Simulator of the Human Intestinal Microbial Ecosystem (SHIME)—the closest simulation of the human gastrointestinal system. It recreates the physiological conditions of digestion (food uptake, peristalsis, digestive enzymes, pancreatic and bile acids) and time spent in each step to represent the dynamic microbial conditions of the human gastrointestinal tract.
Strengthens your gut at the source for lasting relief.
In a 12-week study of adults who occasionally experienced digestive disorders.
Before and after taking DS-01, the number of beneficial bacteria in the gut increased 4.6 times (in a 12-week study of adults who occasionally experienced indigestion).
The increase was most significant in core beneficial bacteria genera such as Bifidobacterium and Lactobacillus, with simultaneous improvement in strain diversity and a more balanced and stable gut microbiota structure. This change directly translates into improved digestive function; subjects experienced a reduction of over 60% in the frequency of bloating and flatulence, significantly improved bowel regularity and stool consistency scores, and a marked increase in intestinal motility.
As beneficial bacteria colonize and proliferate, the intestinal barrier function is continuously enhanced. This not only reduces the recurrence of intestinal discomfort, but also provides a solid intestinal foundation for immune regulation and metabolic balance through gut-body connections, allowing the body to gradually recover to a healthy homeostasis starting from the core digestive organs.
Safety + Testing
DS-01 is held to a superior standard of quality and safety, undergoing 50+ checkpoints throughout the production process testing for purity, potency, and contaminants.
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Vegan
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No Preservatives
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No Binders
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Dairy-Tested
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Gluten-Tested
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Nut-Tested
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Soy-Tested
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Shellfish-Tested
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Sesame-Tested
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Corn-Tested
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Prop. 65 Compliant
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Glyphosate / AMPA-Tested
DS-01 outperforms other probiotics
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Others | |
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24 clinically studied probiotic strains |
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Engineered for precision delivery to the colon |
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Third-party tested for pesticides, allergens, and heavy metals |
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Vegan, gluten- and nut-tested, low FODMAP |
Clinical Trials
Only about 16% of supplements are clinically tested.DS-01® has been clinically proven in 4 gold-standard, double-blind placebo controlled clinical trials.In addition, DS-01®’s probiotic strains have been validated in 10, dose-matched gold-standard clinical trials.
The Impact of Clinical Proof
Double-blind, randomized, placebo-controlled trials (DBRCTs) are the gold standard in scientific research for various reasons, including:
- Bias elimination
- Control for placebo-effect
- Validated efficacy
- Regulatory compliance
By testing DS-01 as a full formulation, the entire product is meticulously inspected and validated for safety, tolerability, and efficacy.
Digestive Health
DS-01 is formulated to improve the frequency of your bowel movements, as well as increase stool consistency and comfort during evacuation.
Clinical Trial Results
- In a 30-Day Study on select DS-01 strains, adults experiencing gastrointestinal troubles saw significant improvement in bowel movement frequency, consistency, and ease of defecation, compared to placebo.
- DS-01's strains also demonstrated improvements in burning, discomfort, sense of complete emptying, and abdominal bloating.
Immune Health
DS-01 promotes a strong, resilient immune system. Dedicated strains support the gut-immune axis, which allows these systems to communicate effectively and strengthen overall immune function.
Clinical Trial Results
- In a 12-week study using select DS-01 strains, participants showed a reduction in microbial translocation across the intestinal epithelial barrier and favorable circulating Th17:Treg and Th1:Th2 ratios. These findings indicate an appropriately responsive immunologic profile.
Skin Health
DS-01 is formulated with dedicated strains that support the gut-skin axis, which plays a key role in regulating inflammatory pathways between the gut and skin.
Clinical Trial Results
- A 4-week study found DS-01's prebiotic significantly reduced wrinkle severity and demonstrated an overall shift in the skin microbiome, indicating a beneficial effect on the gut-skin axis.
- A 12-week study of adults with functionally and aesthetically bothersome skin showed DS-01 strains not only improved skin appearance, but also raised quality of life scores.
Heart Health
DS-01 is formulated to help maintain healthy, in-range cholesterol and blood pressure levels. Select strains promote the production of beneficial metabolites in the gut, which supports healthy liver function and cholesterol balance.
Clinical Trial Results
- In a 12-week study, DS-01 strains helped probiotic group participants maintain healthy, baseline LDL-C levels, compared to a placebo group that experienced LDL-C increases.
- Additionally, the probiotic group demonstrated reinforcement of HDL-cholesterol and evidence of healthy triglyceride management within the 6-12 week timeframe.
Gut Barrier
DS-01 is formulated to strengthen and support a resilient gut barrier. Select strains replenish microflora in the gut in order to help rebuild a weakened microbiome.
Clinical Trial Results
- In a 12-week study using select DS-01 strains, adults experiencing increased gut permeability showed significant reductions in circulating lipopolysaccharide (LPS), a marker of increased epithelial permeability, the cells which comprise the gut barrier.
- DS-01 significantly reduced urinary lactulose excretion starting at 7 days and after 3 months of ongoing DS-01 use, compared to the placebo group— indicating both immediate and continued support for gut barrier integrity and function.
Seed Probiotics Review FAQs
Can I take Seed while pregnant or breastfeeding?
Pregnant women, breastfeeding women, or people taking special medications such as immunosuppressants should consult a medical professional in advance, even if they have no history of allergies (product label: "Pregnant women/breastfeeding women should consult a doctor").
Do l need to refrigerate Seed?
No! Seed’s DS-01 is Shelf-stable for up to 18 months, so no refrigeration is needed.
Can I take Seed with vitamins or food?
Yes, you can take Seed with your vitamins or on an empty stomach. Personally, I take it first thing in the morning on an empty stomach, and it works great for me.
Why can Seed DS-01 probiotics target the colon precisely?
This product utilizes patented ViaCap dual-capsule delivery technology to ensure probiotics precisely reach the colon.
The specific mechanism is as follows:
- The outer capsule contains prebiotics, released in the upper GI tract, pre-preparing a nutrient environment for beneficial gut bacteria;
- The inner capsule uses a special plant-based material (hydroxypropyl methylcellulose + water), which can resist damage from stomach acid, digestive enzymes, and bile, releasing probiotics only in the colon.
What are the fundamental differences between its delivery technology and that of ordinary probiotics?
The essential difference between DS-01 and ordinary probiotics is:
Ordinary probiotics are mostly in single capsule or powder form, lacking protective mechanisms. Approximately 80%-90% of strains are inactivated by gastric acid and digestive enzymes in the upper digestive tract (stomach, upper small intestine) and cannot reach the colon; while DS-01, through its "dual-capsule staged release" design, has been validated by the SHIME intestinal simulator test, showing a significantly improved strain survival rate, enabling it to truly colonize and exert its effects in the colon.
What precautions should be taken when taking this product for people with dietary restrictions (such as vegetarian or gluten-free) or a history of allergies (such as nut or dairy allergies)?
People in this group should pay attention to "ingredient safety" and "compatibility testing" before taking the product.
- Dietary suitability guaranteed: Clearly compatible with 5 dietary patterns: vegetarian, vegan, ketogenic, gluten-free, and intermittent fasting. Contains no animal-derived ingredients (capsules are made of pure natural ingredients and contain no gelatin). Meets gluten-free dietary standards (third-party gluten testing shows content < 20ppm, meeting international gluten-free standards).
- Allergy risk control: Tests were conducted on 14 categories of common allergens defined by EFSA, including dairy products, nuts (peanuts, tree nuts), soy, shellfish, sesame, corn, gluten, etc., and all results were "not detected"; at the same time, there are no preservatives or binders, avoiding the risk of allergies to additives;
- Special Notes: If you have a rare history of allergy to "Indian pomegranate extract" or "organic rice fiber/extract", you should consult a doctor first. Pregnant women, breastfeeding women, or people who are taking special medications such as immunosuppressants should consult a medical professional in advance, even if they have no history of allergy (the product label says "pregnant women/breastfeeding women should consult a doctor").